Information for site staff in the UK
People admitted to hospital with influenza pneumonia or community-acquired pneumonia may be invited to participate in the RECOVERY trial. Current active comparisons are listed on the home page. The trial is designed to have the least possible impact on NHS staff. You will find Frequently Asked Questions on the site set-up page.
See below for update alerts.
update alerts
4 april 2024
The final two COVID-19 comparisons (sotrovimab and high dose dexamethasone) closed to recruitment on 31 March. Any sotrovimab remaining at sites should be disposed of according to local policy. We will share results from these comparisons when they become available.
RECOVERY will remain open to the influenza and CAP comparisons, which are planned to continue until at least June 2026.
All sites are invited to take part in the RECOVERY CAP comparison, including sites taking part in ASPECT (see ASPECT & RECOVERY coordination plan).
All sites are invited to take part in the RECOVERY influenza comparisons at locations where the RECOVERY or REMAP-CAP influenza comparisons are not already open (see REMAP-CAP & RECOVERY collaboration plan).
We would be grateful if you could let us know if your site is interested in opening the RECOVERY influenza or CAP comparisons as soon as possible, even if you don’t plan recruitment to start until Autumn/Winter 2024.
27 february 2024
A coordination plan has been agreed between the ASPECT community-acquired pneumonia trial and RECOVERY, which can be found on the site teams page.
1 december 2023
Substantial amendment 33 has been approved, which introduces a new dexamethasone comparison for patients with community-acquired pneumonia (CAP). This involves new versions of the protocol (V27.0) and adult PIS-ICF (V26.0). We are asking sites to implement this amendment on 8th January 2024, whether or not they plan to open the CAP comparison then. SA33 documents are available from the Regulatory documents page now, and the rest of the website will be updated with these on 8th January. Please ensure that any previous document versions are destroyed after this date.
STUDY PROTOCOL
The RECOVERY Trial protocol is available for use by investigators everywhere to design their own randomised trials that could help identify effective treatments for COVID-19.