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The RECOVERY Trial: how to save more than a million lives

A range of promising but unproven treatments have been suggested for the treatment of COVID-19 and influenza.

The RECOVERY Trial has found four treatments that are effective for severe COVID-19 and is currently testing the following suggested treatments to find out whether they are more effective in helping people recover than the standard care that all patients receive:

For COVID-19

  • sotrovimab (an antibody treatment against the spike protein)
  • high dose corticosteroids (an immune suppressant) in the sickest patients who need mechanical breathing support.

For influenza

  • oseltamivir (an antiviral treatment)
  • baloxavir (an antiviral treatment)
  • low dose corticosteroids

Data from the trial are regularly reviewed so that any effective treatment can be identified quickly and made available to all patients. Please see our news page for results that RECOVERY has found. The RECOVERY Trial team will constantly review information on new drugs and include promising ones in the trial.  

Letters from the Chief Medical Officers

The Chief Medical Officers of England, Wales, Scotland and Northern Ireland, and the NHS Medical Director, have written to all doctors strongly encouraging participation in the national randomised trials in COVID-19 of which RECOVERY is one. You can read the letters by following the links below. Please pass them on to your colleagues.

The importance of increasing recruitment

The importance of COVID-19 clinical trials

Recruiting patients for clinical trials for Covid-19 therapeutics

The RECOVERY Trial is registered at ISRCTN50189673 
EU Clinical Trials Register: EudraCT 2020-001113-21
Clinical NCT04381936